{ "date": "2026-05-29", "generated_at": "2026-05-29T10:54:57.623Z", "publish_status": "published", "window": { "start": "2026-05-28T05:15:00.000Z", "end": "2026-05-29T07:15:00.000Z", "lookback_hours": 26 }, "automation_mode": "Codex LLM editorial ranking with deterministic pre-score", "candidate_count": 107, "collected_candidate_count": 133, "duplicate_candidate_count": 26, "sections": { "papers": [], "patents": [], "biotech_news": [] }, "lower_priority": { "papers": [ { "id": "pubmed:42206665", "source_type": "papers", "source": "PubMed", "pmid": "42206665", "doi": "10.1002/cpt.70319", "headline": "Clinical Validation of a QSP Model for ISB 2001, a Trispecific T Cell Engager to Support Optimal FIH Study Design in RRMM Patients.", "summary": "Clinical pharmacology and therapeutics. Clin Pharmacol Ther. 2026-05-28", "url": "https://pubmed.ncbi.nlm.nih.gov/42206665/", "published_date": "2026-05-28", "publication_date": "2026-05-28", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-28T07:44:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Published May 28; added to PubMed May 28", "journal": "Clinical pharmacology and therapeutics", "authors": [ "Chandralayam Ayyappa Menon V", "Matsuura T", "Holkova B", "Gudi GS", "Drake A", "Pihlgren M", "van der Graaf PH", "Gn S", "Garton A", "Perro M", "Konto C", "Pacaud L" ], "keywords": [ "pubmed", "pubmed pdat", "pubmed crdt" ], "score": 18, "match_reason": "Generic T-cell engager modality: t cell engager", "rank_features": { "positive_signal_count": 1, "title_signal_count": 1, "field_anchor_count": 0, "raw_score": 18 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "biorxiv:10.64898/2026.05.25.727598", "source_type": "papers", "source": "bioRxiv", "doi": "10.64898/2026.05.25.727598", "preprint_id": "biorxiv:10.64898/2026.05.25.727598", "headline": "UcTCRp: a TCRβ-based framework for quantitative MAIT- and iNKT-associated repertoire-state profiling", "summary": "MAIT and iNKT cells are conventionally identified using invariant or semi-invariant TCR chains, antigen-loaded tetramers, or transcriptomic phenotypes. These requirements limit their detection in public and clinical immune-repertoire datasets that contain only TCR{beta} sequences.", "url": "https://doi.org/10.64898/2026.05.25.727598", "published_date": "2026-05-28", "published_date_precision": "date", "journal": "bioRxiv", "authors": [ "Chen, L.", "Li, Y.", "Shan, S.", "Wang, K.", "Feng, C.", "Dou, Y.", "Xu, Q.", "Cai, L.", "Wang, H.", "Wang, H.", "Bo, X.", "Zhang, J." ], "keywords": [ "biorxiv", "bioinformatics" ], "score": 9, "match_reason": "Low-specificity pMHC/TCR field anchor: tcr", "rank_features": { "positive_signal_count": 1, "title_signal_count": 1, "field_anchor_count": 1, "raw_score": 9 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42206712", "source_type": "papers", "source": "PubMed", "pmid": "42206712", "doi": "", "headline": "[Research progress on the correlation between erythrocyte alloimmunity and HLA gene polymorphism].", "summary": "Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi", "url": "https://pubmed.ncbi.nlm.nih.gov/42206712/", "published_date": "2026-05-28", "publication_date": "", "published_date_source": "pubmed_created", "published_date_precision": "date", "indexed_at": "2026-05-28T07:53:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Added to PubMed May 28", "journal": "Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology", "authors": [ "Li X", "Su P" ], "keywords": [ "pubmed", "pubmed crdt" ], "score": 9, "match_reason": "Low-specificity pMHC/TCR field anchor: hla", "rank_features": { "positive_signal_count": 1, "title_signal_count": 1, "field_anchor_count": 0, "raw_score": 9 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42207091", "source_type": "papers", "source": "PubMed", "pmid": "42207091", "doi": "10.1111/tan.70755", "headline": "Identification of a Novel HLA-B*56:106 Allele in an Indian Individual Using Next-Generation Sequencing.", "summary": "HLA. HLA", "url": "https://pubmed.ncbi.nlm.nih.gov/42207091/", "published_date": "2026-05-28", "publication_date": "", "published_date_source": "pubmed_created", "published_date_precision": "date", "indexed_at": "2026-05-28T10:33:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Added to PubMed May 28", "journal": "HLA", "authors": [ "Chowdhry M", "Yadav A", "Kumar D" ], "keywords": [ "pubmed", "pubmed crdt" ], "score": 9, "match_reason": "Low-specificity pMHC/TCR field anchor: hla", "rank_features": { "positive_signal_count": 1, "title_signal_count": 1, "field_anchor_count": 0, "raw_score": 9 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42207135", "source_type": "papers", "source": "PubMed", "pmid": "42207135", "doi": "10.1111/tan.70768", "headline": "Identification of the Novel HLA-A*02:1269 Allele by Next-Generation Sequencing.", "summary": "HLA. HLA", "url": "https://pubmed.ncbi.nlm.nih.gov/42207135/", "published_date": "2026-05-28", "publication_date": "", "published_date_source": "pubmed_created", "published_date_precision": "date", "indexed_at": "2026-05-28T10:42:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Added to PubMed May 28", "journal": "HLA", "authors": [ "Blumenthal N", "Bruniquet K", "Pédron B", "Nel I" ], "keywords": [ "pubmed", "pubmed crdt" ], "score": 9, "match_reason": "Low-specificity pMHC/TCR field anchor: hla", "rank_features": { "positive_signal_count": 1, "title_signal_count": 1, "field_anchor_count": 0, "raw_score": 9 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42207110", "source_type": "papers", "source": "PubMed", "pmid": "42207110", "doi": "10.1111/tan.70760", "headline": "The Novel HLA-DQB1*06:553 Allele Identified in Male by Next-Generation Sequencing.", "summary": "HLA. HLA", "url": "https://pubmed.ncbi.nlm.nih.gov/42207110/", "published_date": "2026-05-28", "publication_date": "", "published_date_source": "pubmed_created", "published_date_precision": "date", "indexed_at": "2026-05-28T10:33:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Added to PubMed May 28", "journal": "HLA", "authors": [ "Ge J", "Eravelli V", "Brown Y", "Park C", "Ruiz P" ], "keywords": [ "pubmed", "pubmed crdt" ], "score": 9, "match_reason": "Low-specificity pMHC/TCR field anchor: hla", "rank_features": { "positive_signal_count": 1, "title_signal_count": 1, "field_anchor_count": 0, "raw_score": 9 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42207493", "source_type": "papers", "source": "PubMed", "pmid": "42207493", "doi": "10.1111/tan.70770", "headline": "Third-Generation Nanopore Sequencing for Post-Transplant Chimerism Monitoring.", "summary": "HLA. HLA", "url": "https://pubmed.ncbi.nlm.nih.gov/42207493/", "published_date": "2026-05-28", "publication_date": "", "published_date_source": "pubmed_created", "published_date_precision": "date", "indexed_at": "2026-05-28T11:23:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Added to PubMed May 28", "journal": "HLA", "authors": [ "Pedini P", "Rateau E", "Maioli S", "Cherouat N", "Basire A", "Barlogis V", "Picard C", "Frassati C" ], "keywords": [ "pubmed", "pubmed crdt" ], "score": 6, "match_reason": "Low-specificity pMHC/TCR field anchor: hla", "rank_features": { "positive_signal_count": 1, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 6 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "journal-rss:nature communications current issue:10.1038/s41467-026-73789-4", "source_type": "papers", "source": "Nature Communications RSS", "doi": "10.1038/s41467-026-73789-4", "headline": "Controlled sweat generation via ultrasound stimulation integrated in a wearable device", "summary": "Nature Communications, Published online: 29 May 2026; doi:10.1038/s41467-026-73789-4 Reliable sweat induction remains a challenge for wearable sweat biosensing. Here, the authors develop a skin-conformal wearable device that uses ultrasound to induce sweat under resting conditions for electrochemical biomarker tracking.", "url": "https://doi.org/10.1038/s41467-026-73789-4", "published_date": "2026-05-29", "published_date_precision": "date", "journal": "Nature Communications", "authors": [ "Litong Chen", "Benxing Su", "Geng Zhong", "Jing Wang", "Yongxiang Ji", "Zhongzeng Zhou", "Xuecheng He", "Tailin Xu" ], "journal_feed_source": "Nature Communications current issue", "keywords": [ "journal rss", "Nature Communications", "Nature Communications current issue" ], "score": 3, "match_reason": "Watchlist hits: Roche", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 3 }, "entities": { "companies": [ "Roche" ], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "biorxiv:10.64898/2026.05.25.727622", "source_type": "papers", "source": "bioRxiv", "doi": "10.64898/2026.05.25.727622", "preprint_id": "biorxiv:10.64898/2026.05.25.727622", "headline": "Biofunctional 2D Graphitic Carbon Nitride-Hydrogel Heterointerfaces for Electrochemical Detection of Interleukin-6 toward Septic Cardiomyopathy Diagnostics in Clinical Biofluids", "summary": "Interleukin-6 (IL-6) is a key pro-inflammatory cytokine closely associated with sepsis progression and septic cardiomyopathy (SCM), a severe clinical condition characterized by acute cardiac dysfunction and high mortality in critically ill patients.", "url": "https://doi.org/10.64898/2026.05.25.727622", "published_date": "2026-05-28", "published_date_precision": "date", "journal": "bioRxiv", "authors": [ "Agarwal, P.", "Yadav, A. K.", "Singh, A.", "Yadav, S. K.", "Praneeth, N. V. S.", "Bhatia, D. D." ], "keywords": [ "biorxiv", "bioengineering" ], "score": 3, "match_reason": "Watchlist hits: Roche", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 3 }, "entities": { "companies": [ "Roche" ], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "biorxiv:10.64898/2026.05.25.727605", "source_type": "papers", "source": "bioRxiv", "doi": "10.64898/2026.05.25.727605", "preprint_id": "biorxiv:10.64898/2026.05.25.727605", "headline": "BIFO: A Biological Information Flow Ontology for Directed Propagation in Heterogeneous Biomedical Knowledge Graphs", "summary": "Biomedical knowledge graphs integrate heterogeneous data by connecting many entity types through many relationship types. Computational analyses that propagate signal across these graphs (random walks, diffusion, and message passing) implicitly assume that every traversable edge can carry a biological signal.", "url": "https://doi.org/10.64898/2026.05.25.727605", "published_date": "2026-05-28", "published_date_precision": "date", "journal": "bioRxiv", "authors": [ "Taylor, D. M.", "Mohseni Ahooyi, T.", "Stear, B.", "Zhang, Y.", "Lahiri, A. M.", "Simmons, J. A.", "Chinwalla, A.", "Nemarich, C.", "Callahan, T. J.", "Silverstein, J. C." ], "keywords": [ "biorxiv", "bioinformatics" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 1, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "medrxiv:10.64898/2026.05.27.26354202", "source_type": "papers", "source": "medRxiv", "doi": "10.64898/2026.05.27.26354202", "preprint_id": "medrxiv:10.64898/2026.05.27.26354202", "headline": "Intravital mid-infrared biosensing by normalized spatial probing of self-referenced optothermal signals", "summary": "We present a compact pump-and-probe mid-infrared Optothermal Spectrometer (OTHES) equipped with Spatial Probing and Autocorrection (SPAC) optimized for robust intravital application in humans. SPAC-OTHES facilitates alignment stability and spectral comparability across different measurement sessions involving different skin types.", "url": "https://doi.org/10.64898/2026.05.27.26354202", "published_date": "2026-05-28", "published_date_precision": "date", "journal": "medRxiv", "authors": [ "Berger, C. G.", "Puttfarcken, B.", "Qiu, J.", "Hauer, I.", "Herr, S.", "Juestel, D.", "Pleitez, M. A." ], "keywords": [ "medrxiv", "endocrinology" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 1, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "biorxiv:10.1101/2024.08.16.608170", "source_type": "papers", "source": "bioRxiv", "doi": "10.1101/2024.08.16.608170", "preprint_id": "biorxiv:10.1101/2024.08.16.608170", "headline": "Oncolytic vaccinia virus expression of a defined peptide-MHCI complex as a precision cancer immunotherapy platform", "summary": "Oncolytic viruses are immunotherapeutic agents that selectively replicate in and kill tumour cells with the goal of promoting anti-cancer immune responses. Vaccinia virus (VACV) is a strong oncolytic virus candidate as it infects a wide range of cancer cells, is amenable to genetic tailoring and induces potent, long-lasting immunity.", "url": "https://doi.org/10.1101/2024.08.16.608170", "published_date": "2026-05-28", "published_date_precision": "date", "journal": "bioRxiv", "authors": [ "Komant, S. J.", "Wang, J. L.", "Favis, N.", "Alex, C.", "Evans, D. H.", "Noyce, R. S.", "Baldwin, T. A." ], "keywords": [ "biorxiv", "immunology" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 1, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "journal-rss:nature chemical biology current issue:10.1038/s41589-026-02233-x", "source_type": "papers", "source": "Nature Chemical Biology RSS", "doi": "10.1038/s41589-026-02233-x", "headline": "A potent alternative cysteine production pathway allows reductase independence", "summary": "Nature Chemical Biology, Published online: 29 May 2026; doi:10.1038/s41589-026-02233-x To obtain the semi-essential amino acid cysteine, cells assimilate its oxidized form, cystine, and then reduce its disulfide bond.", "url": "https://doi.org/10.1038/s41589-026-02233-x", "published_date": "2026-05-29", "published_date_precision": "date", "journal": "Nature Chemical Biology", "authors": [], "journal_feed_source": "Nature Chemical Biology current issue", "keywords": [ "journal rss", "Nature Chemical Biology", "Nature Chemical Biology current issue" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "journal-rss:nature reviews genetics current issue:10.1038/s41576-026-00974-y", "source_type": "papers", "source": "Nature Reviews Genetics RSS", "doi": "10.1038/s41576-026-00974-y", "headline": "Advancing the applications of liquid biopsies in oncology", "summary": "Nature Reviews Genetics, Published online: 29 May 2026; doi:10.1038/s41576-026-00974-y In this Review, Valpione et al. discuss how the current applications of liquid biopsies in precision oncology might be expanded to provide a more holistic and personalized view of cancer and to improve cancer diagnosis and treatment.", "url": "https://doi.org/10.1038/s41576-026-00974-y", "published_date": "2026-05-29", "published_date_precision": "date", "journal": "Nature Reviews Genetics", "authors": [ "Sara Valpione", "Alexandra Clipson", "Dominic G. Rothwell", "Caroline Dive", "Florent Mouliere" ], "journal_feed_source": "Nature Reviews Genetics current issue", "keywords": [ "journal rss", "Nature Reviews Genetics", "Nature Reviews Genetics current issue" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "journal-rss:nature communications current issue:10.1038/s41467-026-73839-x", "source_type": "papers", "source": "Nature Communications RSS", "doi": "10.1038/s41467-026-73839-x", "headline": "Anthropogenic climate change accelerates the onset of global flood timing", "summary": "Nature Communications, Published online: 29 May 2026; doi:10.1038/s41467-026-73839-x The study shows that climate warming alters global flood timing, producing regionally divergent shifts that affect over half of the world and challenge traditional disaster preparedness.", "url": "https://doi.org/10.1038/s41467-026-73839-x", "published_date": "2026-05-29", "published_date_precision": "date", "journal": "Nature Communications", "authors": [ "Wei Qi", "Yanli Liu", "Xin Jiang", "Junguo Liu" ], "journal_feed_source": "Nature Communications current issue", "keywords": [ "journal rss", "Nature Communications", "Nature Communications current issue" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "journal-rss:nature current issue:10.1038/s41586-026-10605-5", "source_type": "papers", "source": "Nature RSS", "doi": "10.1038/s41586-026-10605-5", "headline": "Author Correction: US oil and gas system emissions from nearly one million aerial site measurements", "summary": "Nature, Published online: 29 May 2026; doi:10.1038/s41586-026-10605-5 Author Correction: US oil and gas system emissions from nearly one million aerial site measurements", "url": "https://doi.org/10.1038/s41586-026-10605-5", "published_date": "2026-05-29", "published_date_precision": "date", "journal": "Nature", "authors": [ "Evan D. Sherwin", "Jeffrey S. Rutherford", "Zhan Zhang", "Yuanlei Chen", "Erin B. Wetherley", "Petr V. Yakovlev", "Elena S. F. Berman", "Brian B. Jones", "Daniel H. Cusworth", "Andrew K. Thorpe", "Alana K. Ayasse", "Riley M. Duren" ], "journal_feed_source": "Nature current issue", "keywords": [ "journal rss", "Nature", "Nature current issue" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "biorxiv:10.64898/2026.05.26.726543", "source_type": "papers", "source": "bioRxiv", "doi": "10.64898/2026.05.26.726543", "preprint_id": "biorxiv:10.64898/2026.05.26.726543", "headline": "Circadian misalignment underlies immune escape in breast cancer", "summary": "Circadian regulation shapes tissue physiology, yet how it organizes cellular and molecular dynamics within the tumor microenvironment (TME) and influences tumor immunity remains unclear.", "url": "https://doi.org/10.64898/2026.05.26.726543", "published_date": "2026-05-29", "published_date_precision": "date", "journal": "bioRxiv", "authors": [ "Liang, C.", "Liu, Z.", "Xu, X.", "Xu, Z.", "Zhang, Q.", "Zhang, T.", "Mangan, R. J.", "Xiu, B.", "Wu, G.", "Akhshi, T.", "Sandusky, Z. M.", "Gray, G. K.", "Zhang, N.", "Kuziel, G.", "Traphagen, N. A.", "Fass, S. B.", "Grayson, A.", "Ho, L.-L.", "Gu, S. S.", "Wang, S.", "Sheng, Z. Z.", "Zhang, Y.", "Adib, E.", "Chen, T.", "Jeselsohn, R.", "Kellis, M.", "Brown, M." ], "keywords": [ "biorxiv", "cancer biology" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "journal-rss:nature communications current issue:10.1038/s41467-026-73820-8", "source_type": "papers", "source": "Nature Communications RSS", "doi": "10.1038/s41467-026-73820-8", "headline": "Directed trilithiation enables entropically stabilized heavy-atom-centered triangulenes", "summary": "Nature Communications, Published online: 29 May 2026; doi:10.1038/s41467-026-73820-8 Embedding heavy main-group elements at the core of rigid π-conjugated frameworks has long been recognized as an ideal strategy for enhanced stability yet synthetic realization has remained elusive.", "url": "https://doi.org/10.1038/s41467-026-73820-8", "published_date": "2026-05-29", "published_date_precision": "date", "journal": "Nature Communications", "authors": [ "Hajime Gotoh", "Soichiro Nakatsuka", "Keisuke Kinoshita", "Jiping Hao", "Takuji Hatakeyama" ], "journal_feed_source": "Nature Communications current issue", "keywords": [ "journal rss", "Nature Communications", "Nature Communications current issue" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "biorxiv:10.64898/2026.01.30.702929", "source_type": "papers", "source": "bioRxiv", "doi": "10.64898/2026.01.30.702929", "preprint_id": "biorxiv:10.64898/2026.01.30.702929", "headline": "Dual roles for influenza A virus PA-X in evasion of innate and adaptive immunity in the human airway epithelium", "summary": "The mechanisms of immune evasion of influenza A virus are key to its success as an infectious agent. To replicate effectively, influenza A virus must suppress both early innate immune responses, like antiviral type I and III interferons, and adaptive immune responses.", "url": "https://doi.org/10.64898/2026.01.30.702929", "published_date": "2026-05-29", "published_date_precision": "date", "journal": "bioRxiv", "authors": [ "Setaro, A. C.", "Thomas, C. A.", "Gaglia, M. M." ], "keywords": [ "biorxiv", "microbiology" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "journal-rss:nature reviews immunology current issue:10.1038/s41577-026-01317-y", "source_type": "papers", "source": "Nature Reviews Immunology RSS", "doi": "10.1038/s41577-026-01317-y", "headline": "Eosinophils shape barrier immunity during reproduction", "summary": "Nature Reviews Immunology, Published online: 29 May 2026; doi:10.1038/s41577-026-01317-y Eosinophils remodel the maternal intestine during pregnancy and lactation, promoting goblet cell differentiation and strengthening barrier immunity.", "url": "https://doi.org/10.1038/s41577-026-01317-y", "published_date": "2026-05-29", "published_date_precision": "date", "journal": "Nature Reviews Immunology", "authors": [ "Alexandra Flemming" ], "journal_feed_source": "Nature Reviews Immunology current issue", "keywords": [ "journal rss", "Nature Reviews Immunology", "Nature Reviews Immunology current issue" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "journal-rss:communications biology current issue:10.1038/s42003-026-10376-9", "source_type": "papers", "source": "Communications Biology RSS", "doi": "10.1038/s42003-026-10376-9", "headline": "Extrinsic MMPs drive epithelial shape change via basal extracellular matrix disassembly in the Drosophila wing disc", "summary": "Communications Biology, Published online: 29 May 2026; doi:10.1038/s42003-026-10376-9 A study shows that epithelial shape changes in the Drosophila wing disc are driven by basal extracellular matrix disassembly induced by MMP activity in neighboring non-epithelial tissues.", "url": "https://doi.org/10.1038/s42003-026-10376-9", "published_date": "2026-05-29", "published_date_precision": "date", "journal": "Communications Biology", "authors": [ "Chigusa Hinata", "Hirotatsu Nakagawa", "Shigenori Nonaka", "Katsuya Nozaki", "Yoshikatsu Sato", "Shizue Ohsawa" ], "journal_feed_source": "Communications Biology current issue", "keywords": [ "journal rss", "Communications Biology", "Communications Biology current issue" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "journal-rss:nature communications current issue:10.1038/s41467-026-73782-x", "source_type": "papers", "source": "Nature Communications RSS", "doi": "10.1038/s41467-026-73782-x", "headline": "Grayscale projection two-photon lithography using sub-diffraction motifs for ultrafast and precise nanoscale 3D printing", "summary": "Nature Communications, Published online: 29 May 2026; doi:10.1038/s41467-026-73782-x The ability to precisely tune light intensity within projected images can massively scale up sub-100 nm additive manufacturing. Kim and Saha show how optical diffraction can be leveraged to achieve this with a single pulse of femtosecond laser.", "url": "https://doi.org/10.1038/s41467-026-73782-x", "published_date": "2026-05-29", "published_date_precision": "date", "journal": "Nature Communications", "authors": [ "Harnjoo Kim", "Sourabh K. Saha" ], "journal_feed_source": "Nature Communications current issue", "keywords": [ "journal rss", "Nature Communications", "Nature Communications current issue" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "journal-rss:nature communications current issue:10.1038/s41467-026-73406-4", "source_type": "papers", "source": "Nature Communications RSS", "doi": "10.1038/s41467-026-73406-4", "headline": "Highly potent C-type nanoantibodies neutralize Nipah and Hendra viruses by cavity filling on fusion glycoprotein", "summary": "Nature Communications, Published online: 29 May 2026; doi:10.1038/s41467-026-73406-4 Currently, no approved vaccines or antiviral drugs are available against Nipah virus.", "url": "https://doi.org/10.1038/s41467-026-73406-4", "published_date": "2026-05-29", "published_date_precision": "date", "journal": "Nature Communications", "authors": [ "Shengdong Wang", "Guibo Rao", "Xinghai Zhang", "Yanfeng Yao", "Li Chen", "Shaohong Chen", "Haiwei Zhang", "Hang Liu", "Miaoyu Chen", "Wujian Li", "Sheng Cao", "Sandra Chiu" ], "journal_feed_source": "Nature Communications current issue", "keywords": [ "journal rss", "Nature Communications", "Nature Communications current issue" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "journal-rss:nature current issue:10.1038/d41586-026-01393-z", "source_type": "papers", "source": "Nature RSS", "doi": "10.1038/d41586-026-01393-z", "headline": "How jazz boosts my creativity in physics", "summary": "Nature, Published online: 29 May 2026; doi:10.1038/d41586-026-01393-z Stephon Alexander says his passion for musical improvisation helps him to understand and teach complex ideas.", "url": "https://doi.org/10.1038/d41586-026-01393-z", "published_date": "2026-05-29", "published_date_precision": "date", "journal": "Nature", "authors": [ "Dom Byrne" ], "journal_feed_source": "Nature current issue", "keywords": [ "journal rss", "Nature", "Nature current issue" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "journal-rss:nature immunology current issue:10.1038/s41590-026-02539-x", "source_type": "papers", "source": "Nature Immunology RSS", "doi": "10.1038/s41590-026-02539-x", "headline": "Immune-competent new approach methodologies for a hybrid future", "summary": "Nature Immunology, Published online: 29 May 2026; doi:10.1038/s41590-026-02539-x In a shifting regulatory landscape that increasingly favors organ-on-chip and human cell-based systems, embedding immune complexity is essential to advance new approach methodologies beyond reductionist models and toward a hybrid ecosystem that integrates an...", "url": "https://doi.org/10.1038/s41590-026-02539-x", "published_date": "2026-05-29", "published_date_precision": "date", "journal": "Nature Immunology", "authors": [ "Vance Soares", "Victor M. Quiroz", "Martin Trapecar", "Deok-Ho Kim", "Joshua C. Doloff" ], "journal_feed_source": "Nature Immunology current issue", "keywords": [ "journal rss", "Nature Immunology", "Nature Immunology current issue" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "journal-rss:nature methods current issue:10.1038/s41592-026-03116-8", "source_type": "papers", "source": "Nature Methods RSS", "doi": "10.1038/s41592-026-03116-8", "headline": "iPS cells: history made and history in the making", "summary": "Nature Methods, Published online: 29 May 2026; doi:10.1038/s41592-026-03116-8 The method to reprogram fully differentiated cells using transcription factors retools cells — and has retooled many a scientist’s trajectory. Here, researchers comment on this ‘remodeling’ and the future they foresee.", "url": "https://doi.org/10.1038/s41592-026-03116-8", "published_date": "2026-05-29", "published_date_precision": "date", "journal": "Nature Methods", "authors": [ "Vivien Marx" ], "journal_feed_source": "Nature Methods current issue", "keywords": [ "journal rss", "Nature Methods", "Nature Methods current issue" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "journal-rss:nature communications current issue:10.1038/s41467-026-73686-w", "source_type": "papers", "source": "Nature Communications RSS", "doi": "10.1038/s41467-026-73686-w", "headline": "Metabolic feedbacks drive population dynamics and can lead to oscillations among leaf bacteria", "summary": "Nature Communications, Published online: 29 May 2026; doi:10.1038/s41467-026-73686-w Plant-associated bacteria engage in complex metabolic interactions. Here authors used microfluidics and computational modeling to identify molecular drivers of these interactions and disentangle their contributions to emergent ecological dynamics.", "url": "https://doi.org/10.1038/s41467-026-73686-w", "published_date": "2026-05-29", "published_date_precision": "date", "journal": "Nature Communications", "authors": [ "Alan R. Pacheco", "Giovanni Stefano Ugolini", "Simon H. Rüdisser", "Andrea Zamuner", "Miriam Bortfeld-Miller", "Patrick Kiefer", "Franziska Oschmann", "Samuel G. V. Charlton", "Michael Berger", "Tommaso Redaelli", "Miguel Ángel Salazar", "Ilija Dukovski" ], "journal_feed_source": "Nature Communications current issue", "keywords": [ "journal rss", "Nature Communications", "Nature Communications current issue" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "biorxiv:10.64898/2026.05.26.727850", "source_type": "papers", "source": "bioRxiv", "doi": "10.64898/2026.05.26.727850", "preprint_id": "biorxiv:10.64898/2026.05.26.727850", "headline": "Multi omics reveals mesodermal fate bias and enables predictive cell state control in human pluripotent stem cell biomanufacturing", "summary": "Despite accelerating interest in using human induced pluripotent stem cell (hiPSC)-derived products for disease modeling and therapeutic development, there is substantial evidence that conventional culture approaches do not fully recapitulate natural embryonic nor lineage committed states.", "url": "https://doi.org/10.64898/2026.05.26.727850", "published_date": "2026-05-29", "published_date_precision": "date", "journal": "bioRxiv", "authors": [ "Colter, J.", "Dang, T.", "Young, D.", "Dufour, A.", "Lewis, I.", "Murari, K.", "Kallos, M. S." ], "keywords": [ "biorxiv", "bioengineering" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "journal-rss:nature communications current issue:10.1038/s41467-026-73693-x", "source_type": "papers", "source": "Nature Communications RSS", "doi": "10.1038/s41467-026-73693-x", "headline": "Noisy quantum learning theory", "summary": "Nature Communications, Published online: 29 May 2026; doi:10.1038/s41467-026-73693-x Expected quantum advantages in learning unknown system properties usually rely on idealized scenarios.", "url": "https://doi.org/10.1038/s41467-026-73693-x", "published_date": "2026-05-29", "published_date_precision": "date", "journal": "Nature Communications", "authors": [ "Jordan Cotler", "Weiyuan Gong", "Ishaan Kannan" ], "journal_feed_source": "Nature Communications current issue", "keywords": [ "journal rss", "Nature Communications", "Nature Communications current issue" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "journal-rss:nature medicine current issue:10.1038/s41591-026-04451-1", "source_type": "papers", "source": "Nature Medicine RSS", "doi": "10.1038/s41591-026-04451-1", "headline": "Pathogenic germline variants identify elevated cancer risk in pediatric patients referred for genetic testing", "summary": "Nature Medicine, Published online: 29 May 2026; doi:10.1038/s41591-026-04451-1 Through large-scale genomic analysis, we show that pathogenic germline variants in pediatric cancer-predisposition genes are associated with increased subsequent tumor risk, highlighting their value for counseling and surveillance.", "url": "https://doi.org/10.1038/s41591-026-04451-1", "published_date": "2026-05-29", "published_date_precision": "date", "journal": "Nature Medicine", "authors": [], "journal_feed_source": "Nature Medicine current issue", "keywords": [ "journal rss", "Nature Medicine", "Nature Medicine current issue" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "journal-rss:communications medicine current issue:10.1038/s43856-026-01695-3", "source_type": "papers", "source": "Communications Medicine RSS", "doi": "10.1038/s43856-026-01695-3", "headline": "Predict neuromuscular performance in human epidural electrical stimulation: phase 1 trial interim results", "summary": "Communications Medicine, Published online: 29 May 2026; doi:10.1038/s43856-026-01695-3 Li et al. integrate computational modeling and AI-based optimization to personalize epidural electrical stimulation for individuals with spinal cord injury.", "url": "https://doi.org/10.1038/s43856-026-01695-3", "published_date": "2026-05-29", "published_date_precision": "date", "journal": "Communications Medicine", "authors": [ "Hongda Li", "Yunyue Wei", "Yanan Sui", "Xi Zhang", "Xuesong Luo", "Boyang Zhang", "Bozhi Ma" ], "journal_feed_source": "Communications Medicine current issue", "keywords": [ "journal rss", "Communications Medicine", "Communications Medicine current issue" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "biorxiv:10.64898/2026.05.27.728291", "source_type": "papers", "source": "bioRxiv", "doi": "10.64898/2026.05.27.728291", "preprint_id": "biorxiv:10.64898/2026.05.27.728291", "headline": "Single-cell analysis of Plasmodium falciparum transcripts after drug perturbation identifies feedback regulation as well as increased transmission potential", "summary": "Gene expression analysis in malaria parasites has been used to define transcriptional regulatory networks but has been used less frequently to characterize parasite response to drug treatment or to show how parasites may evade killing.", "url": "https://doi.org/10.64898/2026.05.27.728291", "published_date": "2026-05-29", "published_date_precision": "date", "journal": "bioRxiv", "authors": [ "Godinez-Macias, K. P.", "Calla, J.", "Jepsen, K.", "Winzeler, E. A." ], "keywords": [ "biorxiv", "microbiology" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "journal-rss:nature communications current issue:10.1038/s41467-026-73656-2", "source_type": "papers", "source": "Nature Communications RSS", "doi": "10.1038/s41467-026-73656-2", "headline": "Sterically-extended asymmetric conjugated hole-selective layer for perovskite/silicon tandem solar cells", "summary": "Nature Communications, Published online: 29 May 2026; doi:10.1038/s41467-026-73656-2 Carbazole-based monolayers aid perovskite–silicon tandem solar cells yet preventing aggregation while maintaining charge transport on textured silicon is challenging. Yan et al.", "url": "https://doi.org/10.1038/s41467-026-73656-2", "published_date": "2026-05-29", "published_date_precision": "date", "journal": "Nature Communications", "authors": [ "Tingxia Yan", "Chenxu He", "Chi Li", "Xinhua Ouyang" ], "journal_feed_source": "Nature Communications current issue", "keywords": [ "journal rss", "Nature Communications", "Nature Communications current issue" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "journal-rss:nature reviews immunology current issue:10.1038/s41577-026-01315-0", "source_type": "papers", "source": "Nature Reviews Immunology RSS", "doi": "10.1038/s41577-026-01315-0", "headline": "Why pigs might help us develop better vaccines and drugs against influenza virus", "summary": "Nature Reviews Immunology, Published online: 29 May 2026; doi:10.1038/s41577-026-01315-0 Advances in genetic engineering, immunological tools, single-cell transcriptomics and in vivo imaging have strengthened the usefulness of pigs in influenza research.", "url": "https://doi.org/10.1038/s41577-026-01315-0", "published_date": "2026-05-29", "published_date_precision": "date", "journal": "Nature Reviews Immunology", "authors": [ "John P. Driver", "Daniela S. Rajao", "Anika Singanayagam", "Montserrat Torremorell", "Elma Tchilian" ], "journal_feed_source": "Nature Reviews Immunology current issue", "keywords": [ "journal rss", "Nature Reviews Immunology", "Nature Reviews Immunology current issue" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42206702", "source_type": "papers", "source": "PubMed", "pmid": "42206702", "doi": "", "headline": "[Unveiling the mechanisms of baicalein in regulating allergic contact dermatitis: A network pharmacology approach].", "summary": "Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi", "url": "https://pubmed.ncbi.nlm.nih.gov/42206702/", "published_date": "2026-05-28", "publication_date": "", "published_date_source": "pubmed_created", "published_date_precision": "date", "indexed_at": "2026-05-28T07:53:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Added to PubMed May 28", "journal": "Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology", "authors": [ "Fan H", "Jing Y", "Yang J", "Wang S", "Wei Y", "Lyu Y", "Zhuang R" ], "keywords": [ "pubmed", "pubmed crdt" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "journal-rss:science latest articles:10.1126/science.aeb2672", "source_type": "papers", "source": "Science RSS", "doi": "10.1126/science.aeb2672", "headline": "A Hormone Cell Atlas maps the human endocrine system at cellular resolution", "summary": "Science, Ahead of Print.", "url": "https://doi.org/10.1126/science.aeb2672", "published_date": "2026-05-28", "published_date_precision": "date", "journal": "Science", "authors": [ "Lijiang Fei, Isabel Huang-Doran, Katherine Lawler, Yizhou Yu, Jan Patrick Pett, Kevin M. Méndez-Acevedo, Dinesh Shah, Jaume Margalef-Rieres, Joseph S. Pohlman, Batuhan Cakir, Madelyn R. Moy, Robert G. Legg, Chuan Xu, Ken To, Duy Pham, Alexander V. Predeus, Ruth Hanssen, Tessa M. Cacciottolo, Rakesh K. Kapuge, Krzysztof Polanski, Amanda J. Oliver, Sarah A. Teichmann, I. Sadaf Farooqi" ], "journal_feed_source": "Science latest articles", "keywords": [ "journal rss", "Science", "Science latest articles" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "biorxiv:10.64898/2026.05.27.728110", "source_type": "papers", "source": "bioRxiv", "doi": "10.64898/2026.05.27.728110", "preprint_id": "biorxiv:10.64898/2026.05.27.728110", "headline": "A neuroimmune IL-13 axis is associated with human enteric nervous system development", "summary": "The mechanisms governing maturation of the human enteric nervous system (ENS) during early postnatal life remain poorly defined. Here, we characterize the transcriptomic, cellular, and functional landscape of the neonatal human ileum and identify a neuro-immune axis associated with ENS expansion.", "url": "https://doi.org/10.64898/2026.05.27.728110", "published_date": "2026-05-28", "published_date_precision": "date", "journal": "bioRxiv", "authors": [ "Goncalves, L. E. D.", "Ghirotto, B.", "Pizano, A.", "Rossdeutsch, L.", "Thoma, O.-M.", "Jacobsen, A.", "Trumet, L.", "Weber, M.", "Rosshart, S. P.", "Besendörfer, M.", "Eckstein, M.", "Schmidt, C.", "Namipashaki, A.", "Yu, H.", "Hao, M. M.", "Stamp, L. A.", "Neurath, M.", "Günther, C.", "Winner, B.", "Hensel, I. V.", "Diez, S." ], "keywords": [ "biorxiv", "neuroscience" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42017804", "source_type": "papers", "source": "PubMed", "pmid": "42017804", "doi": "10.1039/d5nr03936c", "headline": "A novel manganese glycerophosphate vaccine gel elicits broad and durable immunity across an aged and pox virus model.", "summary": "Nanoscale. Nanoscale. 2026-05-28", "url": "https://pubmed.ncbi.nlm.nih.gov/42017804/", "published_date": "2026-05-28", "publication_date": "2026-05-28", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-04-22T09:54:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-04-22", "pubmed_date_note": "Published May 28; added to PubMed Apr 22", "journal": "Nanoscale", "authors": [ "Islam MJ", "Ontiveros-Padilla L", "Ehrenzeller SA", "Middleton DD", "Roque JA 3rd", "Murphy CT", "Lukesh NR", "Hendy DA", "Pena ES", "Stack RN", "Polacheck WJ", "Bachelder EM", "Ainslie KM" ], "keywords": [ "pubmed", "pubmed pdat" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42207301", "source_type": "papers", "source": "PubMed", "pmid": "42207301", "doi": "10.1007/s00428-026-04581-4", "headline": "A rare solid tumor frequently misdiagnosed as lymphoma: primary colonic Epstein-Barr virus-positive inflammatory follicular dendritic cell sarcoma.", "summary": "Virchows Archiv : an international journal of pathology. Virchows Arch. 2026-05-28", "url": "https://pubmed.ncbi.nlm.nih.gov/42207301/", "published_date": "2026-05-28", "publication_date": "2026-05-28", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-28T11:15:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Published May 28; added to PubMed May 28", "journal": "Virchows Archiv : an international journal of pathology", "authors": [ "Xie JL", "Yang HJ", "Zhang ZF", "Yue B", "Zheng GJ", "Wang LH", "Zhou XG", "Zhao C", "Chen GY" ], "keywords": [ "pubmed", "pubmed pdat", "pubmed crdt" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42207554", "source_type": "papers", "source": "PubMed", "pmid": "42207554", "doi": "10.1182/blood.2026033564", "headline": "A reassessment of anti-CAR T-cell expansion strategies.", "summary": "Blood. Blood. 2026-05-28", "url": "https://pubmed.ncbi.nlm.nih.gov/42207554/", "published_date": "2026-05-28", "publication_date": "2026-05-28", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-28T11:43:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Published May 28; added to PubMed May 28", "journal": "Blood", "authors": [ "Bollard CM", "Heslop HE" ], "keywords": [ "pubmed", "pubmed pdat", "pubmed crdt" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "biorxiv:10.64898/2026.01.13.699115", "source_type": "papers", "source": "bioRxiv", "doi": "10.64898/2026.01.13.699115", "preprint_id": "biorxiv:10.64898/2026.01.13.699115", "headline": "Amplified genome editing by in vivo editor production", "summary": "Genome editing enzymes have vast therapeutic potential. However, achieving sufficient delivery in vivo remains a major challenge, because editing machinery is confined to the subset of transfectable cells in a tissue.", "url": "https://doi.org/10.64898/2026.01.13.699115", "published_date": "2026-05-28", "published_date_precision": "date", "journal": "bioRxiv", "authors": [ "Ngo, W.", "Rosas-Rivera, D.", "Wasko, K. M.", "Qiu, L.", "Kang, M. H.", "Gogna, S.", "Zeng, J.", "Hooks, M. T.", "Wu, J. L. Y.", "Li, Z.", "Doudna, J. A." ], "keywords": [ "biorxiv", "bioengineering" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "biorxiv:10.64898/2026.05.25.727443", "source_type": "papers", "source": "bioRxiv", "doi": "10.64898/2026.05.25.727443", "preprint_id": "biorxiv:10.64898/2026.05.25.727443", "headline": "An integrated human forebrain organoid reveals microglia-mediated CD8⁺ T cell recruitment and neuroimmune dysfunction in Alzheimer's disease pathology", "summary": "Genetic evidence implicates immune dysfunction in Alzheimer's disease (AD), yet human-specific neuroimmune mechanisms remain poorly defined. Here, we establish a modular human forebrain organoid platform that systematically integrates iPSC-derived microglia and CD8 T cells to reconstitute multicellular AD pathology.", "url": "https://doi.org/10.64898/2026.05.25.727443", "published_date": "2026-05-28", "published_date_precision": "date", "journal": "bioRxiv", "authors": [ "MA, S." ], "keywords": [ "biorxiv", "bioengineering" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:41734346", "source_type": "papers", "source": "PubMed", "pmid": "41734346", "doi": "10.1182/blood.2025032142", "headline": "Antigen-boosted CD4CAR T cells fail to expand or control viremia in multiple nonhuman primate models of HIV.", "summary": "Blood. Blood. 2026-05-28", "url": "https://pubmed.ncbi.nlm.nih.gov/41734346/", "published_date": "2026-05-28", "publication_date": "2026-05-28", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-02-24T15:54:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-02-24", "pubmed_date_note": "Published May 28; added to PubMed Feb 24", "journal": "Blood", "authors": [ "Maynard LH", "Starke CE", "Poole NH", "Rust BJ", "Zhu H", "Stensland L", "Huang ML", "Pérez-Osorio AC", "Atherley JI", "Einhaus T", "Murray J", "Pampena MB", "Betts MR", "Jerome KR", "Riley JL", "Kiem HP", "Peterson CW" ], "keywords": [ "pubmed", "pubmed pdat" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42206678", "source_type": "papers", "source": "PubMed", "pmid": "42206678", "doi": "10.4081/ejh.2026.4540", "headline": "Astragaloside IV inhibits nasopharyngeal carcinoma progression by inhibiting SATB2/Wnt/PD-L1 pathway and enhancing the killing activity of T cells.", "summary": "European journal of histochemistry : EJH. Eur J Histochem. 2026-05-28", "url": "https://pubmed.ncbi.nlm.nih.gov/42206678/", "published_date": "2026-05-28", "publication_date": "2026-05-28", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-28T07:44:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Published May 28; added to PubMed May 28", "journal": "European journal of histochemistry : EJH", "authors": [ "Zeng Y", "Huang J", "Duan T", "Wang X" ], "keywords": [ "pubmed", "pubmed crdt" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "biorxiv:10.64898/2026.05.27.725267", "source_type": "papers", "source": "bioRxiv", "doi": "10.64898/2026.05.27.725267", "preprint_id": "biorxiv:10.64898/2026.05.27.725267", "headline": "CAR-Engineered Human Hematopoietic Stem Cell Macrophages Control Solid Tumors", "summary": "Chimeric antigen receptor (CAR) T-cells have been a groundbreaking progress in the control of hematological cancers. However, its efficacy in controlling solid tumors has been rather limited, highlighting the importance of new cell-based therapy strategies to curb the progression of solid cancers.", "url": "https://doi.org/10.64898/2026.05.27.725267", "published_date": "2026-05-28", "published_date_precision": "date", "journal": "bioRxiv", "authors": [ "Ramos, R. N." ], "keywords": [ "biorxiv", "immunology" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42207485", "source_type": "papers", "source": "PubMed", "pmid": "42207485", "doi": "10.1007/s12185-026-04229-8", "headline": "Clinical implications of minimal residual disease monitoring in multiple myeloma.", "summary": "International journal of hematology. Int J Hematol. 2026-05-28", "url": "https://pubmed.ncbi.nlm.nih.gov/42207485/", "published_date": "2026-05-28", "publication_date": "2026-05-28", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-28T11:22:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Published May 28; added to PubMed May 28", "journal": "International journal of hematology", "authors": [ "Yoroidaka T" ], "keywords": [ "pubmed", "pubmed pdat", "pubmed crdt" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42207336", "source_type": "papers", "source": "PubMed", "pmid": "42207336", "doi": "10.1007/s12308-026-00707-4", "headline": "Clinicopathological characteristics of a rare group of chronic active Epstein-Barr virus disease involving the gastrointestinal tract.", "summary": "Journal of hematopathology. J Hematop. 2026-05-28", "url": "https://pubmed.ncbi.nlm.nih.gov/42207336/", "published_date": "2026-05-28", "publication_date": "2026-05-28", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-28T11:16:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Published May 28; added to PubMed May 28", "journal": "Journal of hematopathology", "authors": [ "Zheng X", "Zheng Y", "Xie J", "Huang X", "Teng X", "Zhang Y" ], "keywords": [ "pubmed", "pubmed pdat", "pubmed crdt" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "medrxiv:10.64898/2026.05.26.26353629", "source_type": "papers", "source": "medRxiv", "doi": "10.64898/2026.05.26.26353629", "preprint_id": "medrxiv:10.64898/2026.05.26.26353629", "headline": "Deep Learning Spatial Profiling of CD103+CD8+ T Cells and Survival in Rectal Cancer After Neoadjuvant Chemoradiotherapy", "summary": "Background: CD8+ tumor-infiltrating lymphocytes (TILs) are established prognostic markers in colorectal cancer, yet the clinical significance of CD103+CD8+ tissue-resident memory-like (TRM-like) T cells in locally advanced rectal cancer (LARC) after neoadjuvant chemoradiotherapy (NACRT) remains unknown.", "url": "https://doi.org/10.64898/2026.05.26.26353629", "published_date": "2026-05-28", "published_date_precision": "date", "journal": "medRxiv", "authors": [ "Abe, T.", "Yamashita, K.", "Nagasaka, T.", "Fujita, M.", "Ueda, Y.", "Miyake, S.", "Ito, R.", "Adachi, Y.", "Ando, M.", "Tsuneki, T.", "Okazoe, Y.", "Konaka, R.", "Takahashi, T.", "Kagiyama, H.", "Tachibana, T.", "Imai, M.", "Yoshida, T.", "Saito, M.", "Mukohyama, J.", "Kanayama, K.", "Koma, Y.-I.", "Otowa, Y.", "Hasegawa, H.", "Ikeda, T.", "Koterazawa, Y.", "Aoki, T.", "Harada, H.", "Urakawa, N.", "Goto, H.", "Kanaji, S.", "Yanagimoto, H.", "Matsuda, T.", "Takamura, S.", "Yamashita, T.", "Sasaki, R.", "Fukumoto, T.", "Kakeji, Y." ], "keywords": [ "medrxiv", "oncology" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "biorxiv:10.64898/2026.05.25.727705", "source_type": "papers", "source": "bioRxiv", "doi": "10.64898/2026.05.25.727705", "preprint_id": "biorxiv:10.64898/2026.05.25.727705", "headline": "Distinct senescent β-cell senotypes differentially drive islet aging and dysfunction", "summary": "Biological aging greatly impacts the body's ability to handle glucose, and represents a major risk factor the development and progression of type 2 diabetes (T2D).", "url": "https://doi.org/10.64898/2026.05.25.727705", "published_date": "2026-05-28", "published_date_precision": "date", "journal": "bioRxiv", "authors": [ "Iwasaki, K.", "Pan, H.", "M. Dreyfuss, J.", "Jackson, M.", "Domanskyi, S.", "Baker, D.", "Carapeto, P.", "Cahill, C.", "Le, S.", "Hela, F.", "Alcoforado Diniz, J.", "Naim Eryilmaz, G.", "Wu, F.", "Wu, P.-H.", "Yu, B.", "Wirtz, D.", "Espinoza, S.", "Pena, A.", "G. Cigarroa, F.", "Abrahamian, G.", "Woodworth, J. L.", "Adams, P. D.", "Ucar, D.", "Chuang, J. H.", "Wu, Q.", "Garovic, V. D.", "Kirkland, J. L.", "Tchkonia, T.", "Musi, N.", "Kuchel, G. A.", "Robson, P.", "Aguayo-Mazzucato, C." ], "keywords": [ "biorxiv", "cell biology" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42207214", "source_type": "papers", "source": "PubMed", "pmid": "42207214", "doi": "10.1007/s12672-026-05286-5", "headline": "Exploratory multiomics analysis identifies WDR17 as a potential biomarker of tyrosine kinase inhibitor resistance in lung adenocarcinoma.", "summary": "Discover oncology. Discov Oncol. 2026-05-28", "url": "https://pubmed.ncbi.nlm.nih.gov/42207214/", "published_date": "2026-05-28", "publication_date": "2026-05-28", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-28T11:04:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Published May 28; added to PubMed May 28", "journal": "Discover oncology", "authors": [ "Xu Y", "Li L", "Li Z", "Yang Y", "Xing H", "Ma X", "Zhang X" ], "keywords": [ "pubmed", "pubmed pdat", "pubmed crdt" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "medrxiv:10.64898/2026.05.26.26354165", "source_type": "papers", "source": "medRxiv", "doi": "10.64898/2026.05.26.26354165", "preprint_id": "medrxiv:10.64898/2026.05.26.26354165", "headline": "Grounding Language Models in Behavioral Science to Scale Physical Activity Interventions for Hispanic/Latinx Populations", "summary": "Objective: Hispanic/Latinx populations in the U.S. experience higher rates of chronic disease linked to physical inactivity, yet digital health interventions remain largely inaccessible to more than 16 million Hispanic/Latinx adults with limited English proficiency.", "url": "https://doi.org/10.64898/2026.05.26.26354165", "published_date": "2026-05-28", "published_date_precision": "date", "journal": "medRxiv", "authors": [ "Mantena, S. D.", "Johnson, A.", "Schuetz, N.", "Tolas, A.", "Montalvo, S.", "Delgado-SanMartin, J.", "Ramirez Posada, M.", "Du, L.", "Zhang, S.", "Huynh, A. D.", "Oppezzo, M.", "King, A. C.", "Schmiedmayer, P.", "Lawrie, A.", "Rodriguez, F.", "Ashley, E.", "Kim, D. S." ], "keywords": [ "medrxiv", "cardiovascular medicine" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:41592325", "source_type": "papers", "source": "PubMed", "pmid": "41592325", "doi": "10.1182/blood.2025029824", "headline": "High-dimensional spatiotemporal single-cell atlas and 3D imaging of the bone marrow microenvironment during CML progression.", "summary": "Blood. Blood. 2026-05-28", "url": "https://pubmed.ncbi.nlm.nih.gov/41592325/", "published_date": "2026-05-28", "publication_date": "2026-05-28", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-01-27T17:13:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-01-27", "pubmed_date_note": "Published May 28; added to PubMed Jan 27", "journal": "Blood", "authors": [ "Li L", "Rottmann I", "Saeed BR", "Ivison G", "Wei H", "Schroeder JC", "Dunkel G", "Greif K", "Zhang Y", "Makky A", "Ochsenbein AF", "Riether C", "Goltsev Y", "Nolan GP", "Mayer AT", "Weigelin B", "Schürch CM" ], "keywords": [ "pubmed", "pubmed pdat" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:41779733", "source_type": "papers", "source": "PubMed", "pmid": "41779733", "doi": "10.1182/blood.2025032352", "headline": "How I treat HLH-like toxicities after immune effector cell therapy.", "summary": "Blood. Blood. 2026-05-28", "url": "https://pubmed.ncbi.nlm.nih.gov/41779733/", "published_date": "2026-05-28", "publication_date": "2026-05-28", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-03-04T13:33:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-03-04", "pubmed_date_note": "Published May 28; added to PubMed Mar 4", "journal": "Blood", "authors": [ "Johnson WT", "McNerney KO", "Frank MJ", "Shah NN" ], "keywords": [ "pubmed", "pubmed pdat" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "biorxiv:10.1101/2025.09.12.675873", "source_type": "papers", "source": "bioRxiv", "doi": "10.1101/2025.09.12.675873", "preprint_id": "biorxiv:10.1101/2025.09.12.675873", "headline": "IL-22 promotes genesis of small intestinal secretory cells that protect against cholera in mice", "summary": "The diarrheal disease cholera remains a global threat, but there is limited knowledge of the innate immune defenses in the small intestine that protect against the causative agent, Vibrio cholerae.", "url": "https://doi.org/10.1101/2025.09.12.675873", "published_date": "2026-05-28", "published_date_precision": "date", "journal": "bioRxiv", "authors": [ "Suzuki, M.", "Hasegawa, Y.", "Zhang, H.", "Liang, Z.", "Tie, G.", "Shivdasani, R.", "Waldor, M. K." ], "keywords": [ "biorxiv", "microbiology" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42207176", "source_type": "papers", "source": "PubMed", "pmid": "42207176", "doi": "10.1158/1078-0432.CCR-26-0738", "headline": "Intrathecal Allogeneic B7-H3-targeted CAR γδ T Cells for Leptomeningeal Metastasis from Solid Tumors: Safety, Efficacy, and Immunological Dynamics in a Phase 1 Trial.", "summary": "Clinical cancer research : an official journal of the American Association for Cancer Research. Clin Cancer Res. 2026-05-28", "url": "https://pubmed.ncbi.nlm.nih.gov/42207176/", "published_date": "2026-05-28", "publication_date": "2026-05-28", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-28T10:54:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Published May 28; added to PubMed May 28", "journal": "Clinical cancer research : an official journal of the American Association for Cancer Research", "authors": [ "Ma P", "Zhou Y", "Ma W", "Wang Y", "Cai H", "Sui Y", "Zhao L", "Zhang Y", "Wang S", "Li N" ], "keywords": [ "pubmed", "pubmed pdat", "pubmed crdt" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "biorxiv:10.64898/2026.05.25.726449", "source_type": "papers", "source": "bioRxiv", "doi": "10.64898/2026.05.25.726449", "preprint_id": "biorxiv:10.64898/2026.05.25.726449", "headline": "Mapping Genetic Risk Associations to Cellular Contexts via Deep Learning and Biological Ontologies", "summary": "Translating genome-wide association studies (GWAS) signals into trait-relevant cellular contexts remains challenging due to the complexity of the genomic regulatory code and linkage disequilibrium among associated variants.", "url": "https://doi.org/10.64898/2026.05.25.726449", "published_date": "2026-05-28", "published_date_precision": "date", "journal": "bioRxiv", "authors": [ "Margalit, T.", "Levi, H.", "Shamir, R.", "Elkon, R." ], "keywords": [ "biorxiv", "bioinformatics" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "biorxiv:10.64898/2026.05.25.727439", "source_type": "papers", "source": "bioRxiv", "doi": "10.64898/2026.05.25.727439", "preprint_id": "biorxiv:10.64898/2026.05.25.727439", "headline": "MicroRNA-29a enhances and preserves stem-like CD8 T cell differentiation by regulating master epigenetic circuits of exhaustion.", "summary": "CD8 T cells mediate protective immune responses. However, persisting antigens such as chronic viruses or tumors redirect CD8 T cell differentiation to a sub-optimal, epigenetically defined state called exhaustion. Exhausted T cells (TEX) lose their ability to persist long-term and to initiate functional memory responses.", "url": "https://doi.org/10.64898/2026.05.25.727439", "published_date": "2026-05-28", "published_date_precision": "date", "journal": "bioRxiv", "authors": [ "Leng, X.", "Buchness, L. A.", "Rafie, C. I.", "Vlantis, P. I.", "Ristin, S.", "Gallardo, M. A.", "Auwardt, S. L.", "Khatwani, N. K.", "Tan, Y.-D.", "Ban, Y.", "Sologon, C. M.", "Currall, B. B.", "Williams, S. L.", "Van der Jeught, K.", "Datta, J. L.", "Villarino, A. V.", "Telonis, A. G.", "Stelekati, E." ], "keywords": [ "biorxiv", "immunology" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42206847", "source_type": "papers", "source": "PubMed", "pmid": "42206847", "doi": "10.1128/mbio.00772-26", "headline": "Myeloid-derived suppressor cell (MDSC)-like neutrophils induced by pulmonary infection with Coccidioides posadasii exacerbate disease by suppressing CD4(+) T cell immunity.", "summary": "mBio. mBio. 2026-05-28", "url": "https://pubmed.ncbi.nlm.nih.gov/42206847/", "published_date": "2026-05-28", "publication_date": "2026-05-28", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-28T09:02:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Published May 28; added to PubMed May 28", "journal": "mBio", "authors": [ "Abdul-Baki N", "Negron A", "Navarro R", "Campuzano A", "Mendoza Barker M", "Prather ND", "Fidel PL Jr", "Forsthuber TG", "Yu J-J", "Hung C-Y" ], "keywords": [ "pubmed", "pubmed pdat", "pubmed crdt" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42207333", "source_type": "papers", "source": "PubMed", "pmid": "42207333", "doi": "10.1007/s12017-026-08918-9", "headline": "Neuropilins in Multiple Sclerosis: Dual Roles of NRP-1 in Neuroinflammation and Neuroprotection.", "summary": "Neuromolecular medicine. Neuromolecular Med. 2026-05-28", "url": "https://pubmed.ncbi.nlm.nih.gov/42207333/", "published_date": "2026-05-28", "publication_date": "2026-05-28", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-28T11:16:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Published May 28; added to PubMed May 28", "journal": "Neuromolecular medicine", "authors": [ "Goleij P", "Babamohamadi M", "Heidari MM", "Khazeei Tabari MA", "Abolfazli S", "Mohammadi S", "Majma Sanaye P", "Arefnezhad R", "Aschner M", "Khan H", "Rezaei Tavirani M", "Movafagh A" ], "keywords": [ "pubmed", "pubmed pdat", "pubmed crdt" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42206580", "source_type": "papers", "source": "PubMed", "pmid": "42206580", "doi": "10.1111/pim.70086", "headline": "No Evidence for Association Between ICOS (a T-Cell Co-Stimulatory Molecule) Gene Polymorphisms and Anti-MSP-1(19) IgG Response in Venezuelan Endemic Plasmodium vivax Malaria.", "summary": "Parasite immunology. Parasite Immunol", "url": "https://pubmed.ncbi.nlm.nih.gov/42206580/", "published_date": "2026-05-28", "publication_date": "", "published_date_source": "pubmed_created", "published_date_precision": "date", "indexed_at": "2026-05-28T06:54:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Added to PubMed May 28", "journal": "Parasite immunology", "authors": [ "Sevilla RD", "Regalado-Gutiérrez OA", "Wide A", "Puche-Quiñonez R", "Patarroyo MA", "Noya-González O", "Fernández-Mestre M" ], "keywords": [ "pubmed", "pubmed crdt" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "biorxiv:10.64898/2026.05.28.728382", "source_type": "papers", "source": "bioRxiv", "doi": "10.64898/2026.05.28.728382", "preprint_id": "biorxiv:10.64898/2026.05.28.728382", "headline": "Piezo1 links cytoskeletal remodeling to differential YAP and β-catenin signaling in response to mechanical cues", "summary": "Mechanical cues from the extracellular matrix regulate cancer cell behavior, but how these inputs are translated into distinct nuclear signaling responses remains incompletely understood.", "url": "https://doi.org/10.64898/2026.05.28.728382", "published_date": "2026-05-28", "published_date_precision": "date", "journal": "bioRxiv", "authors": [ "Wu, Y.", "Ge, C.", "Su, Z. H.", "You, L.", "Geng, F." ], "keywords": [ "biorxiv", "cell biology" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "biorxiv:10.64898/2026.05.27.728101", "source_type": "papers", "source": "bioRxiv", "doi": "10.64898/2026.05.27.728101", "preprint_id": "biorxiv:10.64898/2026.05.27.728101", "headline": "Plasticity of genetic regulation during cellular learning", "summary": "Even under physiological conditions, cells are exposed to multiple, spatially and temporally complex signals and need to regularly adjust their response to survive and function. At least in some cases, identifying the appropriate response relies on the ability cells to learn from experience.", "url": "https://doi.org/10.64898/2026.05.27.728101", "published_date": "2026-05-28", "published_date_precision": "date", "journal": "bioRxiv", "authors": [ "Heistinger, L.", "Parfenova, I.", "Damenikan, A.", "Michel, A.", "Kornmann, B.", "Sintsova, A.", "Barral, Y." ], "keywords": [ "biorxiv", "cell biology" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42207441", "source_type": "papers", "source": "PubMed", "pmid": "42207441", "doi": "10.1007/s12672-026-05282-9", "headline": "RAS pathway activity subtypes identified by machine learning define prognostic and immune microenvironment characteristics in lung adenocarcinoma.", "summary": "Discover oncology. Discov Oncol. 2026-05-28", "url": "https://pubmed.ncbi.nlm.nih.gov/42207441/", "published_date": "2026-05-28", "publication_date": "2026-05-28", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-28T11:20:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Published May 28; added to PubMed May 28", "journal": "Discover oncology", "authors": [ "Shi Y" ], "keywords": [ "pubmed", "pubmed pdat", "pubmed crdt" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:41734335", "source_type": "papers", "source": "PubMed", "pmid": "41734335", "doi": "10.1182/blood.2026033814", "headline": "Rust BJ, Kean LS, Colonna L, Brandenstein KE, Poole NH, Obenza W, Enstrom MR, Maldini CR, Ellis GI, Fennessey CM, Huang M-L, Keele BF, Jerome KR, Riley JL, Kiem H-P, Peterson CW. Robust expansion of HIV CAR T cells following antigen boosting in ART-suppressed nonhuman primates. Blood. 2020;136(15):1722-1734.", "summary": "Blood. Blood. 2026-05-28", "url": "https://pubmed.ncbi.nlm.nih.gov/41734335/", "published_date": "2026-05-28", "publication_date": "2026-05-28", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-02-24T15:53:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-02-24", "pubmed_date_note": "Published May 28; added to PubMed Feb 24", "journal": "Blood", "authors": [], "keywords": [ "pubmed", "pubmed pdat" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42090447", "source_type": "papers", "source": "PubMed", "pmid": "42090447", "doi": "10.1530/RAF-25-0197", "headline": "SARS-CoV-2 triggers an NF-kB-driven proliferative response in epididymal clear cells of K18-hACE2 mice.", "summary": "Reproduction & fertility. Reprod Fertil. 2026-05-28", "url": "https://pubmed.ncbi.nlm.nih.gov/42090447/", "published_date": "2026-05-28", "publication_date": "2026-05-28", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-06T13:52:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-06", "pubmed_date_note": "Published May 28; added to PubMed May 6", "journal": "Reproduction & fertility", "authors": [ "Da Silva AAS", "Akinsomisoye OS", "Battistone MA", "Cerri PS", "Sasso-Cerri E" ], "keywords": [ "pubmed", "pubmed pdat" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "biorxiv:10.64898/2026.05.24.727572", "source_type": "papers", "source": "bioRxiv", "doi": "10.64898/2026.05.24.727572", "preprint_id": "biorxiv:10.64898/2026.05.24.727572", "headline": "Self-regenerating opsin from reef-building coral", "summary": "Opsins underlie diverse physiological responses to light in animals. In the dark, most opsins bind the chromophore 11-cis retinal, which isomerizes to all-trans form upon light absorption, representing the initial key step in signaling.", "url": "https://doi.org/10.64898/2026.05.24.727572", "published_date": "2026-05-28", "published_date_precision": "date", "journal": "bioRxiv", "authors": [ "Sakai, Y.", "Imamoto, Y.", "Inukai, S.", "Tominaga, Y.", "Sugihara, T.", "Yamashita, T.", "Katayama, K.", "Kakeyama, Y.", "Oka, R.", "Okuno, E.", "Iwasaki, M.", "Kandori, H.", "Koyanagi, M.", "Terakita, A." ], "keywords": [ "biorxiv", "biophysics" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "medrxiv:10.64898/2026.05.05.26352450", "source_type": "papers", "source": "medRxiv", "doi": "10.64898/2026.05.05.26352450", "preprint_id": "medrxiv:10.64898/2026.05.05.26352450", "headline": "Shared Genetics of Hypertension and Preeclampsia Converges on Immune Regulation", "summary": "Background: Hypertension and preeclampsia are clinically distinct, yet biologically related conditions characterized by vascular dysfunction and elevated cardiovascular risk.", "url": "https://doi.org/10.64898/2026.05.05.26352450", "published_date": "2026-05-28", "published_date_precision": "date", "journal": "medRxiv", "authors": [ "Farahat, M. A.", "Abbas, M.", "Melese, M. T.", "Gaye, A." ], "keywords": [ "medrxiv", "genetic and genomic medicine" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "biorxiv:10.64898/2026.05.27.728160", "source_type": "papers", "source": "bioRxiv", "doi": "10.64898/2026.05.27.728160", "preprint_id": "biorxiv:10.64898/2026.05.27.728160", "headline": "STIMscope: centimeter-scale all-optical imaging and patterned optogenetic manipulation at single-cell resolution", "summary": "Linking observation to intervention at cellular resolution makes it possible to move from measuring network activity to testing the contribution of defined neurons or ensembles within the same preparation. All-optical probing provides this capability by combining fluorescence-based readout with targeted optogenetic manipulation.", "url": "https://doi.org/10.64898/2026.05.27.728160", "published_date": "2026-05-28", "published_date_precision": "date", "journal": "bioRxiv", "authors": [ "Chorsi, H.", "Soldado-Magraner, S.", "Jin, Y.", "Soltanalipouryekesammak, I.", "Zheng, A.", "Markovic, D.", "Geschwind, D. H.", "Golshani, P.", "Buonomano, D. V.", "Aharoni, D." ], "keywords": [ "biorxiv", "bioengineering" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42207200", "source_type": "papers", "source": "PubMed", "pmid": "42207200", "doi": "10.1007/s00216-026-06563-6", "headline": "Structural basis of a CDR3-embedded binding mechanism in a nanobody for sensitivity enhancement toward tenuazonic acid.", "summary": "Analytical and bioanalytical chemistry. Anal Bioanal Chem. 2026-05-28", "url": "https://pubmed.ncbi.nlm.nih.gov/42207200/", "published_date": "2026-05-28", "publication_date": "2026-05-28", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-28T11:03:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Published May 28; added to PubMed May 28", "journal": "Analytical and bioanalytical chemistry", "authors": [ "Wei XF", "Fang RY", "Wang CL", "Liang YF", "Li JD", "Wang LT", "Shen YD", "Xu ZL", "Xiao ZL", "Schneider RJ", "Wang H" ], "keywords": [ "pubmed", "pubmed pdat", "pubmed crdt" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "biorxiv:10.64898/2026.05.25.726204", "source_type": "papers", "source": "bioRxiv", "doi": "10.64898/2026.05.25.726204", "preprint_id": "biorxiv:10.64898/2026.05.25.726204", "headline": "Supporting-like cells constitute an alternative steroidogenic lineage conserved in amniotes", "summary": "In mammals, the production of sex hormones is widely considered to depend on the interstitial lineage of the gonad, which differentiates into Leydig cells in males or theca cells in females.", "url": "https://doi.org/10.64898/2026.05.25.726204", "published_date": "2026-05-28", "published_date_precision": "date", "journal": "bioRxiv", "authors": [ "Barbera-Aura, I.", "Chung, W.-Y.", "Dujardin, E.", "Hurtado, A.", "Galmiche, M.", "Mayere, C.", "Guy, M.", "Mandon-Pepin, B.", "Franke, V.", "Jaszczyszyn, Y.", "D. Acemel, R.", "Rudaz, S.", "Mckey, J.", "Nef, S.", "Pailhoux, E.", "G. Lupianez, D." ], "keywords": [ "biorxiv", "developmental biology" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "biorxiv:10.64898/2026.05.25.727700", "source_type": "papers", "source": "bioRxiv", "doi": "10.64898/2026.05.25.727700", "preprint_id": "biorxiv:10.64898/2026.05.25.727700", "headline": "Transient ATR inhibition following ionizing radiation enhances immune-mediated antitumor response and survival", "summary": "Background. ATR activation following DNA damage from cancer treatments such as radiation can mitigate anticancer efficacy, making ATR inhibitors (ATRi) an attractive therapeutic.", "url": "https://doi.org/10.64898/2026.05.25.727700", "published_date": "2026-05-28", "published_date_precision": "date", "journal": "bioRxiv", "authors": [ "Deppas, J.", "Kiesel, B. F.", "Vendetti, F. P.", "Pandya, P.", "Guo, J.", "Cooper, K. L.", "Bakkenist, M. J.", "Tavakoli, M.", "diMayorca, M.", "Islam, N. M.", "Clump, D. A.", "Bakkenist, C. J.", "Beumer, J. H." ], "keywords": [ "biorxiv", "cancer biology" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42204686", "source_type": "papers", "source": "PubMed", "pmid": "42204686", "doi": "10.1177/09636897261449351", "headline": "Role of tumor microenvironment composition and metabolism in lymphoid malignancies and therapeutic strategies.", "summary": "Cell transplantation. Cell Transplant. 2026-05-27", "url": "https://pubmed.ncbi.nlm.nih.gov/42204686/", "published_date": "2026-05-27", "publication_date": "2026-05-27", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-28T00:46:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Published May 27; added to PubMed May 28", "journal": "Cell transplantation", "authors": [ "Niu S", "Liu C", "Deng Q" ], "keywords": [ "pubmed", "pubmed crdt" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42206269", "source_type": "papers", "source": "PubMed", "pmid": "42206269", "doi": "10.1155/humu/8218916", "headline": "A Spatially Constrained Fibroblast-Myeloid Program Associates With Immune Exclusion and Poor Prognosis in Lung Adenocarcinoma.", "summary": "Human mutation. Hum Mutat. 2026-05-26", "url": "https://pubmed.ncbi.nlm.nih.gov/42206269/", "published_date": "2026-05-26", "publication_date": "2026-05-26", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-28T04:46:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Published May 26; added to PubMed May 28", "journal": "Human mutation", "authors": [ "Zhou Y", "Ren X", "Li R", "Chen S", "Wei B", "Shen Y", "Wang X", "Xia Y", "Cao S", "Sun P", "Ding N" ], "keywords": [ "pubmed", "pubmed crdt" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42205540", "source_type": "papers", "source": "PubMed", "pmid": "42205540", "doi": "10.70962/jhi.20260042", "headline": "C5 inhibition restores B cell homeostasis and humoral immunity in CHAPLE disease patients.", "summary": "Journal of human immunity. J Hum Immun. 2026-05-26", "url": "https://pubmed.ncbi.nlm.nih.gov/42205540/", "published_date": "2026-05-26", "publication_date": "2026-05-26", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-28T04:38:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Published May 26; added to PubMed May 28", "journal": "Journal of human immunity", "authors": [ "Tahiat A", "Belbouab R", "Yagoubi A", "Buta Panov S", "Cuollo L", "Djenouhat K", "Bogunovic D" ], "keywords": [ "pubmed", "pubmed crdt" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42205539", "source_type": "papers", "source": "PubMed", "pmid": "42205539", "doi": "10.70962/jhi.20260016", "headline": "Rebooting immunity in congenital athymia: Factors impacting reconstitution with thymus implantation.", "summary": "Journal of human immunity. J Hum Immun. 2026-05-26", "url": "https://pubmed.ncbi.nlm.nih.gov/42205539/", "published_date": "2026-05-26", "publication_date": "2026-05-26", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-28T04:38:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Published May 26; added to PubMed May 28", "journal": "Journal of human immunity", "authors": [ "Cresoe-Ortiz S", "Venturi G", "McCarthy EA", "Stewart-Bates B", "Heimall JR", "Wu EY", "Sleasman JW", "Hall G" ], "keywords": [ "pubmed", "pubmed crdt" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42206267", "source_type": "papers", "source": "PubMed", "pmid": "42206267", "doi": "10.1155/humu/8545428", "headline": "PLSCR3 Deficiency Triggers mtDNA-Driven cGAS-STING Activation to Potentiate Antitumor Immunity in Colorectal Cancer.", "summary": "Human mutation. Hum Mutat. 2026-05-25", "url": "https://pubmed.ncbi.nlm.nih.gov/42206267/", "published_date": "2026-05-25", "publication_date": "2026-05-25", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-28T04:46:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Published May 25; added to PubMed May 28", "journal": "Human mutation", "authors": [ "Ling L", "Wu J", "Bao L", "Liu Z", "Deng Q", "Ji X", "Yu S", "Yu F", "Zhu A", "Xiao Q", "Zheng W" ], "keywords": [ "pubmed", "pubmed crdt" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42205992", "source_type": "papers", "source": "PubMed", "pmid": "42205992", "doi": "10.2147/BLCTT.S582933", "headline": "A Risk Model Using Refined Disease Risk Index and 1-Month NK-Cell Count for Relapse in Children and Adults with T-ALL/LBL After Myeloablative Umbilical Cord Blood Transplantation.", "summary": "Blood and lymphatic cancer : targets and therapy. Blood Lymphat Cancer. 2026-05-22", "url": "https://pubmed.ncbi.nlm.nih.gov/42205992/", "published_date": "2026-05-22", "publication_date": "2026-05-22", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-28T04:42:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Published May 22; added to PubMed May 28", "journal": "Blood and lymphatic cancer : targets and therapy", "authors": [ "Zhao N", "Chi R", "Song K", "Wu Y", "Yan B", "Wang D", "Tang B", "Zhu X" ], "keywords": [ "pubmed", "pubmed crdt" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42206240", "source_type": "papers", "source": "PubMed", "pmid": "42206240", "doi": "10.2147/ITT.S594441", "headline": "An Exploratory in vitro Study of Cytotoxicity and Cytokine Profiling of Cytokine-Induced Killer (CIK) Cells Against HCT-15 Colorectal Cancer (CRC) Cells.", "summary": "ImmunoTargets and therapy. Immunotargets Ther. 2026-05-22", "url": "https://pubmed.ncbi.nlm.nih.gov/42206240/", "published_date": "2026-05-22", "publication_date": "2026-05-22", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-28T04:45:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Published May 22; added to PubMed May 28", "journal": "ImmunoTargets and therapy", "authors": [ "Chin SP", "Nor Arfuzir NN", "Kong VW", "Cheong SK" ], "keywords": [ "pubmed", "pubmed crdt" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42205867", "source_type": "papers", "source": "PubMed", "pmid": "42205867", "doi": "10.2147/IJN.S596277", "headline": "CA9-Targeted Liposomal Delivery of siETS1 Inhibits Clear Cell Renal Cell Carcinoma Progression by Disrupting the ETS1/MYC Regulatory Axis.", "summary": "International journal of nanomedicine. Int J Nanomedicine. 2026-05-22", "url": "https://pubmed.ncbi.nlm.nih.gov/42205867/", "published_date": "2026-05-22", "publication_date": "2026-05-22", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-28T04:41:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Published May 22; added to PubMed May 28", "journal": "International journal of nanomedicine", "authors": [ "Ye Y", "Sun J", "Zhang Y", "Wang S", "Meng Z" ], "keywords": [ "pubmed", "pubmed crdt" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42206198", "source_type": "papers", "source": "PubMed", "pmid": "42206198", "doi": "10.2147/PTT.S608704", "headline": "Paraneoplastic Papuloerythroderma of Ofuji Masquerading as Worsening Psoriasis.", "summary": "Psoriasis (Auckland, N.Z.). Psoriasis (Auckl). 2026-05-22", "url": "https://pubmed.ncbi.nlm.nih.gov/42206198/", "published_date": "2026-05-22", "publication_date": "2026-05-22", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-28T04:45:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Published May 22; added to PubMed May 28", "journal": "Psoriasis (Auckland, N.Z.)", "authors": [ "Hauptman M", "Mehta N", "Wang F", "Lowe L", "Nakamura M" ], "keywords": [ "pubmed", "pubmed crdt" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42207571", "source_type": "papers", "source": "PubMed", "pmid": "42207571", "doi": "10.55563/clinexprheumatol/iushi3", "headline": "Spine structural lesions in ankylosing spondylitis: comparison between radiographic and opportunistic thoraco-abdomino-pelvic computed tomography assessment.", "summary": "Clinical and experimental rheumatology. Clin Exp Rheumatol. 2026-05-21", "url": "https://pubmed.ncbi.nlm.nih.gov/42207571/", "published_date": "2026-05-21", "publication_date": "2026-05-21", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-28T11:53:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Published May 21; added to PubMed May 28", "journal": "Clinical and experimental rheumatology", "authors": [ "Morizot C", "Favre-Félix I", "Mennini A", "Bauer E", "Chary-Valckenaere I", "Loeuille D" ], "keywords": [ "pubmed", "pubmed crdt" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42206145", "source_type": "papers", "source": "PubMed", "pmid": "42206145", "doi": "10.1038/s42256-026-01201-3", "headline": "Immunotherapy drug target identification using machine learning and patient-derived tumour explant validation.", "summary": "Nature machine intelligence. Nat Mach Intell. 2026-05-18", "url": "https://pubmed.ncbi.nlm.nih.gov/42206145/", "published_date": "2026-05-18", "publication_date": "2026-05-18", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-28T04:44:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Published May 18; added to PubMed May 28", "journal": "Nature machine intelligence", "authors": [ "Augustine M", "Nene NR", "Fu H", "Pinder CL", "Ligammari L", "Simpson AP", "Sanz-Fernández I", "Thakkar K", "Qian D", "Fitzsimons E", "Simpson BS", "Vendramin R", "Castro A", "Niederer H", "Turajlic S", "Quezada SA", "McGranahan N", "Watkins C", "Swanton C", "Litchfield K" ], "keywords": [ "pubmed", "pubmed crdt" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42206032", "source_type": "papers", "source": "PubMed", "pmid": "42206032", "doi": "10.3389/fimmu.2026.1783098", "headline": "Early sex-related transcriptional differences in CD8(+) T cells responding to chronic viral infection reveal a sex bias in exhaustion.", "summary": "Frontiers in immunology. Front Immunol. 2026-05-12", "url": "https://pubmed.ncbi.nlm.nih.gov/42206032/", "published_date": "2026-05-12", "publication_date": "2026-05-12", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-28T04:43:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Published May 12; added to PubMed May 28", "journal": "Frontiers in immunology", "authors": [ "Kahia N", "Robertson SM", "Rodriguez M", "Layug PJ", "Vats H", "Kannan K", "Spicer V", "Ozturk-Aptekmann A", "Wilkins O", "Arsenio J" ], "keywords": [ "pubmed", "pubmed crdt" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42206036", "source_type": "papers", "source": "PubMed", "pmid": "42206036", "doi": "10.3389/fimmu.2026.1816695", "headline": "HDAC7 controls anti-viral and anti-tumor immunity by CD8(+) T cells.", "summary": "Frontiers in immunology. Front Immunol. 2026-05-12", "url": "https://pubmed.ncbi.nlm.nih.gov/42206036/", "published_date": "2026-05-12", "publication_date": "2026-05-12", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-28T04:43:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Published May 12; added to PubMed May 28", "journal": "Frontiers in immunology", "authors": [ "Yerinde C", "Keye J", "Hsiao HJ", "Durlanik S", "Freise I", "Nowak F", "Letizia M", "Schlickeiser S", "Obermayer B", "Huck A", "Friedrich M", "Wu H", "Kunkel D", "Kühl AA", "Bauer S", "Thiel A", "Hegazy AN", "Siegmund B", "Glauben R", "Weidinger C" ], "keywords": [ "pubmed", "pubmed crdt" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42205833", "source_type": "papers", "source": "PubMed", "pmid": "42205833", "doi": "10.3389/fmed.2026.1814926", "headline": "Integrase inhibitor-based antiretroviral therapy drives gut microbiota remodeling and immune recovery in HIV infection.", "summary": "Frontiers in medicine. Front Med (Lausanne). 2026-05-12", "url": "https://pubmed.ncbi.nlm.nih.gov/42205833/", "published_date": "2026-05-12", "publication_date": "2026-05-12", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-28T04:41:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Published May 12; added to PubMed May 28", "journal": "Frontiers in medicine", "authors": [ "Karaca B", "Şener A", "Kaptan F", "Ece D", "Örmen B", "Caner A" ], "keywords": [ "pubmed", "pubmed crdt" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42206060", "source_type": "papers", "source": "PubMed", "pmid": "42206060", "doi": "10.3389/fimmu.2026.1792836", "headline": "Multi-omics investigation of perineural invasion in head and neck squamous cell carcinoma: neuroimmune mechanisms and clinical implications.", "summary": "Frontiers in immunology. Front Immunol. 2026-05-12", "url": "https://pubmed.ncbi.nlm.nih.gov/42206060/", "published_date": "2026-05-12", "publication_date": "2026-05-12", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-28T04:43:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Published May 12; added to PubMed May 28", "journal": "Frontiers in immunology", "authors": [ "Deng M", "Lin Y", "Fang C", "Cai J", "Chen C", "Ding J" ], "keywords": [ "pubmed", "pubmed crdt" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42206028", "source_type": "papers", "source": "PubMed", "pmid": "42206028", "doi": "10.3389/fimmu.2026.1738865", "headline": "Real-world comparison of anti-CD20 therapies: efficacy, infections, and immune profiles in a German cohort.", "summary": "Frontiers in immunology. Front Immunol. 2026-05-12", "url": "https://pubmed.ncbi.nlm.nih.gov/42206028/", "published_date": "2026-05-12", "publication_date": "2026-05-12", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-28T04:43:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Published May 12; added to PubMed May 28", "journal": "Frontiers in immunology", "authors": [ "Stögbauer J", "Bewarder M", "Groß L", "Thurner L", "Fassbender K", "Urschel R", "Høgestøl EA", "Nygaard GO", "Harbo HF", "Stüve O", "Pawlitzki M", "Meuth SG", "Sester M", "Groppa S", "Fousse M" ], "keywords": [ "pubmed", "pubmed crdt" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42206048", "source_type": "papers", "source": "PubMed", "pmid": "42206048", "doi": "10.3389/fimmu.2026.1818121", "headline": "Therapeutic cancer vaccines: navigating clinical translation and multimodal synergy.", "summary": "Frontiers in immunology. Front Immunol. 2026-05-12", "url": "https://pubmed.ncbi.nlm.nih.gov/42206048/", "published_date": "2026-05-12", "publication_date": "2026-05-12", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-28T04:43:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Published May 12; added to PubMed May 28", "journal": "Frontiers in immunology", "authors": [ "Chu TH", "Huynh TL", "Phuong LT" ], "keywords": [ "pubmed", "pubmed crdt" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42206029", "source_type": "papers", "source": "PubMed", "pmid": "42206029", "doi": "10.3389/fimmu.2026.1756194", "headline": "Treg-derived IFN-γ supports the differentiation of Th1-Treg in tumor immunity and autoimmunity.", "summary": "Frontiers in immunology. Front Immunol. 2026-05-12", "url": "https://pubmed.ncbi.nlm.nih.gov/42206029/", "published_date": "2026-05-12", "publication_date": "2026-05-12", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-28T04:43:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Published May 12; added to PubMed May 28", "journal": "Frontiers in immunology", "authors": [ "Kuratani A", "Okamoto M", "Arumsari S", "Kobayashi T", "Sasai M", "Yamamoto M" ], "keywords": [ "pubmed", "pubmed crdt" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42206056", "source_type": "papers", "source": "PubMed", "pmid": "42206056", "doi": "10.3389/fimmu.2026.1742723", "headline": "Unlocking the potential: current landscape and future directions of immunotherapy in gastric cancer.", "summary": "Frontiers in immunology. Front Immunol. 2026-05-12", "url": "https://pubmed.ncbi.nlm.nih.gov/42206056/", "published_date": "2026-05-12", "publication_date": "2026-05-12", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-28T04:43:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Published May 12; added to PubMed May 28", "journal": "Frontiers in immunology", "authors": [ "Zhou Y", "Wei L", "Wang L", "Zhang B", "Liang J" ], "keywords": [ "pubmed", "pubmed crdt" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42205925", "source_type": "papers", "source": "PubMed", "pmid": "42205925", "doi": "10.1016/j.ekir.2026.106516", "headline": "Zigakibart Potently Inhibits A Proliferation-Inducing Ligand-Mediated IgA Production, Addressing IgAN Pathogenesis Root Causes.", "summary": "Kidney international reports. Kidney Int Rep. 2026-04-06", "url": "https://pubmed.ncbi.nlm.nih.gov/42205925/", "published_date": "2026-04-06", "publication_date": "2026-04-06", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-28T04:42:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Published Apr 6; added to PubMed May 28", "journal": "Kidney international reports", "authors": [ "Dulos J", "Kreijtz J", "Vink P", "Cotton V", "Kuo JJ", "Lo J", "Jansen W", "Bakker J", "Driessen L", "Guadagnoli M", "van Zandvoort P", "Warncke M", "Medema JP", "Barratt J", "van Eenennaam H", "Van Elsas A" ], "keywords": [ "pubmed", "pubmed crdt" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42205417", "source_type": "papers", "source": "PubMed", "pmid": "42205417", "doi": "10.1002/wjo2.70037", "headline": "The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis.", "summary": "World journal of otorhinolaryngology - head and neck surgery. World J Otorhinolaryngol Head Neck Surg. 2025-08-17", "url": "https://pubmed.ncbi.nlm.nih.gov/42205417/", "published_date": "2025-08-17", "publication_date": "2025-08-17", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-28T04:36:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Published Aug 17; added to PubMed May 28", "journal": "World journal of otorhinolaryngology - head and neck surgery", "authors": [ "Li DL", "Li Y", "Jiang YJ", "Zhang GH", "Chang LH" ], "keywords": [ "pubmed", "pubmed crdt" ], "score": 0, "match_reason": "No high-specificity pMHC/TCR ranking signal detected.", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 0 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "biorxiv:10.64898/2026.05.25.727656", "source_type": "papers", "source": "bioRxiv", "doi": "10.64898/2026.05.25.727656", "preprint_id": "biorxiv:10.64898/2026.05.25.727656", "headline": "STING dampens the unfolded protein response to enable the presentation of self-antigens on MHC-I during inflammation.", "summary": "A growing body of evidence supports the contribution of the long-lasting adaptive immune system in Parkinson's disease (PD). We showed that the PD-associated protein PINK1 negatively regulates the presentation of mitochondrial antigens (MitAP) on MHC-I molecules.", "url": "https://doi.org/10.64898/2026.05.25.727656", "published_date": "2026-05-28", "published_date_precision": "date", "journal": "bioRxiv", "authors": [ "Fahmy, A. M.", "Ahmadi, A.", "Lanoix, J.", "Cannon, T.", "Badr Elemeery, m. N.", "Hernandez Paredes, C.", "Barrette, B.", "Bonneil, E.", "Zhong Xu, Y.", "Ibrahim, M.", "Arango-Duque, G.", "Audemard, E. O.", "Lemieux, S.", "Chevet, E.", "Schurr, E.", "Pierre, P.", "Gruenheid, S.", "Thibault, P.", "McBride, H. M.", "Desjardins, M." ], "keywords": [ "biorxiv", "immunology" ], "score": 0, "match_reason": "Low-specificity pMHC/TCR field anchor: mhc | Downranked for Non-therapeutic broad immunology: inflammation", "rank_features": { "positive_signal_count": 1, "title_signal_count": 1, "field_anchor_count": 0, "raw_score": -9 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "biorxiv:10.64898/2026.05.01.716870", "source_type": "papers", "source": "bioRxiv", "doi": "10.64898/2026.05.01.716870", "preprint_id": "biorxiv:10.64898/2026.05.01.716870", "headline": "Tissue-adapted NK cells shape pathogenic cDC1 niches in early arthritis", "summary": "Chronic forms of autoimmune arthritis, including juvenile idiopathic arthritis (JIA), are characterised by persistent synovial inflammation. While adaptive mechanisms are well-studied, the innate networks driving early joint disease remain poorly defined.", "url": "https://doi.org/10.64898/2026.05.01.716870", "published_date": "2026-05-29", "published_date_precision": "date", "journal": "bioRxiv", "authors": [ "Knight, O. C.", "Giordano, C.", "von Stuckrad, A. S. L.", "Winning, C.", "Bolton, C.", "Mahony, C. B.", "Croft, A. P.", "Mashreghi, M.-F.", "Kallinich, T.", "Rückert, T.", "Romagnani, C." ], "keywords": [ "biorxiv", "immunology" ], "score": 0, "match_reason": "Downranked for Non-therapeutic broad immunology: autoimmune, inflammation", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": -12 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "biorxiv:10.64898/2026.05.25.727767", "source_type": "papers", "source": "bioRxiv", "doi": "10.64898/2026.05.25.727767", "preprint_id": "biorxiv:10.64898/2026.05.25.727767", "headline": "FOXP3-engineered regulatory T cells restore intestinal barrier integrity in Crohn's disease enteroids via PDGF-AA", "summary": "Epithelial regeneration and barrier integrity are impaired in inflammatory bowel diseases, including Crohn's disease (CD), yet current therapies largely target immune inflammation without directly promoting mucosal repair.", "url": "https://doi.org/10.64898/2026.05.25.727767", "published_date": "2026-05-28", "published_date_precision": "date", "journal": "bioRxiv", "authors": [ "Saini, N.", "Ojo, B. A.", "Bozza, N.", "Ramachandran, A.", "Gahlot, P.", "Lopez-Rivera, J. A.", "Tran, T.", "Sokzini, P.", "Meyer, H.", "Dunn, J. C. Y.", "Roncarolo, M. G.", "Rosen, M. J.", "Bacchetta, R." ], "keywords": [ "biorxiv", "immunology" ], "score": 0, "match_reason": "Downranked for Non-therapeutic broad immunology: inflammation", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": -12 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "biorxiv:10.64898/2026.05.26.728058", "source_type": "papers", "source": "bioRxiv", "doi": "10.64898/2026.05.26.728058", "preprint_id": "biorxiv:10.64898/2026.05.26.728058", "headline": "Modeling Prenatal Immune Activation in Human Brain Organoids Uncovers IL-6-Dependent Interneuron Dysmaturation", "summary": "Prenatal inflammation has been associated with an increased likelihood of the child developing neurodevelopmental conditions, such as autism spectrum disorder (ASD). Several pro-inflammatory cytokines are significantly upregulated and play critical roles during immune activation, with interleukin-6 (IL-6) being particularly prominent.", "url": "https://doi.org/10.64898/2026.05.26.728058", "published_date": "2026-05-28", "published_date_precision": "date", "journal": "bioRxiv", "authors": [ "Papetti, A. V.", "Ma, Z.", "NG, M.", "Jin, M.", "Levison, S. W.", "Jiang, P." ], "keywords": [ "biorxiv", "neuroscience" ], "score": 0, "match_reason": "Downranked for Non-therapeutic broad immunology: inflammation", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": -12 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "biorxiv:10.64898/2026.05.27.726087", "source_type": "papers", "source": "bioRxiv", "doi": "10.64898/2026.05.27.726087", "preprint_id": "biorxiv:10.64898/2026.05.27.726087", "headline": "IGF1 modulates lesional skin inflammation in checkpoint inhibitor-induced lichen planus", "summary": "Immune checkpoint inhibitor-induced lichen planus (ICI-LP) is a cutaneous immune related adverse event (irAE) that shares key clinicopathologic features with spontaneous lichen planus (LP) but differs histologically and in the sex distribution of its incidence, and may therefore reflect a distinct tissue inflammatory state.", "url": "https://doi.org/10.64898/2026.05.27.726087", "published_date": "2026-05-28", "published_date_precision": "date", "journal": "bioRxiv", "authors": [ "Hornick, N. I.", "Billo, A.", "Fey, R. M.", "Hawkins, R. M.", "Muhaj, F. F.", "Richards, K. N.", "Patel, A. B.", "Schenkel, J. M.", "Pauken, K. E.", "Moran, A. E." ], "keywords": [ "biorxiv", "immunology" ], "score": 0, "match_reason": "Downranked for Non-therapeutic broad immunology: inflammation", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": -18 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "pubmed:42206386", "source_type": "papers", "source": "PubMed", "pmid": "42206386", "doi": "10.1161/CIRCULATIONAHA.126.079304", "headline": "Integrative Molecular Analyses of Inflammatory and Autoimmune Signals in Cardiac Sarcoidosis.", "summary": "Circulation. Circulation. 2026-05-28", "url": "https://pubmed.ncbi.nlm.nih.gov/42206386/", "published_date": "2026-05-28", "publication_date": "2026-05-28", "published_date_source": "publication", "published_date_precision": "date", "indexed_at": "2026-05-28T05:03:00.000Z", "indexed_at_source": "entrez", "pubmed_added_date": "2026-05-28", "pubmed_date_note": "Published May 28; added to PubMed May 28", "journal": "Circulation", "authors": [ "Neyazi M", "Venturini G", "Brown KJ", "Choi Y", "Gorham JM", "Layton OG", "Verma A", "Wang AJ", "Gross RT", "McDonough BA", "Mendiola Pla M", "Viveiros A", "DeLaughter DM", "DePalma SR", "Kim Y", "Reichart D", "Wakimoto H", "Elledge SJ", "Divakaran S", "Mitchell RN", "Koh J", "Park JB", "Bowles DE", "Glass C", "Oudit GY", "Seidman JG", "Seidman CE" ], "keywords": [ "pubmed", "pubmed pdat", "pubmed crdt" ], "score": 0, "match_reason": "Downranked for Non-therapeutic broad immunology: autoimmune", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": -18 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "biorxiv:10.64898/2026.05.25.727733", "source_type": "papers", "source": "bioRxiv", "doi": "10.64898/2026.05.25.727733", "preprint_id": "biorxiv:10.64898/2026.05.25.727733", "headline": "Nucleic acid turnover and lipid remodeling distinguish T cell activation and exhaustion states via label-free Raman spectroscopy", "summary": "T cell exhaustion impairs immune control of chronic diseases including tuberculosis, HIV, malaria, and cancer. Its clinical implications are vast, predicting HIV-associated malignancy and treatment response and limiting the efficacy of cell therapies.", "url": "https://doi.org/10.64898/2026.05.25.727733", "published_date": "2026-05-28", "published_date_precision": "date", "journal": "bioRxiv", "authors": [ "Morales, M.", "Premachandran, S.", "Ravichandran, S.", "Tadesse, L. F." ], "keywords": [ "biorxiv", "biophysics" ], "score": 0, "match_reason": "Downranked for Generic T cell biology without antigen specificity: t cell exhaustion", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": -18 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "biorxiv:10.64898/2026.05.28.724702", "source_type": "papers", "source": "bioRxiv", "doi": "10.64898/2026.05.28.724702", "preprint_id": "biorxiv:10.64898/2026.05.28.724702", "headline": "Vagus nerve stimulation limits colonic inflammation through distinct neuroimmune circuitry shaped by inflammatory history", "summary": "Bidirectional communication between the nervous and immune systems has been demonstrated to limit or enhance immune cell function across organ systems and conditions.", "url": "https://doi.org/10.64898/2026.05.28.724702", "published_date": "2026-05-28", "published_date_precision": "date", "journal": "bioRxiv", "authors": [ "Sanchez, K.", "Park, J.", "Tay, E.", "Pore, G. M.", "Wagner, A.", "Lee, S.", "Li, J.", "Mirza, A.", "Reardon, C." ], "keywords": [ "biorxiv", "immunology" ], "score": 0, "match_reason": "Downranked for Non-therapeutic broad immunology: inflammation", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": -18 }, "entities": { "companies": [], "targets": [], "modalities": [], "hla": [], "programs": [] } } ], "patents": [], "biotech_news": [ { "id": "news:https://www.biopharmadive.com/news/gsk-ionis-bepirovirsen-hepatitis-b-nejm-study-results/821341/", "source_type": "biotech_news", "source": "BioPharma Dive", "headline": "GSK, Ionis unveil data for hepatitis B drug touted as ‘functional cure’", "summary": "The findings supporting bepirovirsen were deemed a “historic moment” by physicians and validate a drug that has “clear blockbuster potential,” according to one analyst.", "url": "https://www.biopharmadive.com/news/gsk-ionis-bepirovirsen-hepatitis-b-nejm-study-results/821341/", "published_date": "2026-05-28T16:01:00.000Z", "published_date_precision": "datetime", "company_name": "", "drug_name": "", "event_type": "news", "primary_source": "BioPharma Dive", "keywords": [ "news", "BioPharma Dive", "news" ], "secondary_coverage": [], "score": 3, "match_reason": "Watchlist hits: GSK", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 3 }, "entities": { "companies": [ "GSK" ], "targets": [], "modalities": [], "hla": [], "programs": [] } }, { "id": "news:https://www.statnews.com/2026/05/28/biotech-news-asco-preview-2026-all-eyes-on-pancreatic-cancer/?utm_campaign=rss", "source_type": "biotech_news", "source": "STAT Biotech", "headline": "STAT+: Ahead of ASCO, all eyes on pancreatic cancer", "summary": "Strong results from GSK's hepatitis B drug, engineered heart patches, and more biotech news from The Readout", "url": "https://www.statnews.com/2026/05/28/biotech-news-asco-preview-2026-all-eyes-on-pancreatic-cancer/?utm_campaign=rss", "published_date": "2026-05-28T13:21:44.000Z", "published_date_precision": "datetime", "company_name": "", "drug_name": "", "event_type": "news", "primary_source": "STAT Biotech", "keywords": [ "news", "STAT Biotech", "news" ], "secondary_coverage": [], "score": 3, "match_reason": "Watchlist hits: GSK", "rank_features": { "positive_signal_count": 0, "title_signal_count": 0, "field_anchor_count": 0, "raw_score": 3 }, "entities": { "companies": [ "GSK" ], "targets": [], "modalities": [], "hla": [], "programs": [] } } ] }, "llm_adjustments": [], "collection_errors": [ "Endpoints News feed failed: https://endpts.com/feed/ failed with 403", "EPO_OPS_CONSUMER_KEY/EPO_OPS_CONSUMER_SECRET are not configured; EPO OPS patent ingestion skipped.", "LENS_API_TOKEN is not configured; patent ingestion skipped." ], "profile_version": 5 }